Glenn Close

as Cruella de Vil

Gérard Depardieu

as Jean Pierre Le Pelt

Ioan Gruffudd

as Kevin Shepherd

Alice Evans

as Chloe Simon

Tim McInnerny

as Alonzo

Eric Idle

as Waddlesworth (voice)

Ben Crompton

as Ewan

Carol MacReady

as Agnes

Ian Richardson

as Mr. Torte

Jim Carter

as Detective Armstrong

Ron Cook

as Mr. Button

Timothy West

as Judge

David Horovitch

as Dr. Pavlov

Dick Brannick

as Pavlov's Assistant

Mike Hayley

as Constable

Nicholas Hutchison

as Reporter

Tim Willcox

as ITN Reporter

June Watson

as Prison Warden

Tony Bluto

as Photocopier Repairman

Tessa Vale

as Ticket Seller

John Styles

as Punch & Judy Man

Kerry Shale

as Le Pelt's Assistant

Thierry Lawson

as Le Pelt's Assistant

Hugh Futcher

as Brakeman

Charles Simon

as Lord Carnivore

Dorothea Phillips

as Mrs. Mirthless

Delphine Annaiis

as Paris Poodle Lady

Sherwood Ball

as Singer (uncredited)

Macéo Bhardwaj

as Audience Member (uncredited)

JB Blanc

as Police Captain (uncredited)

Ian Boo Khoo

as Passenger at Station (uncredited)

Julia Bridgeman

as Schoolgirl / Puppy (voice; uncredited)

Greg Bronson

as Luncheon Attendee (uncredited)

Martin Brown

as TV News Sound Recordist (uncredited)

Rene Costa

as Paparazzi (uncredited)

Leilani Holmes

as Orient Express Passenger (uncredited)

Karen Kennedy

as Social Worker / Driver (uncredited)

Suzy Kewer

as French Model (uncredited)

David Keyes

as Waddlesworth (voice; uncredited)

Jake Lanning

as Delivery Man (uncredited)

Jonathan Lucas

as Newscaster (voice; uncredited)

Jack Mason

as Boy on Climbing Frame (uncredited)

Ann Mills

as Fashion Show Editor (uncredited)

Adriana Nima

as Dottie (uncredited)

James Payne

as Taxi Driver (uncredited)

Brett Reylander

as Chef (uncredited)

Nigel Rixon

as Bus Driver (uncredited)