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Cast (50)
Danny Trejo
as Machete
Mel Gibson
as Voz
Demián Bichir
as Mendez
Amber Heard
as Miss San Antonio
Michelle Rodriguez
as Luz
Sofía Vergara
as Desdemona
Charlie Sheen
as Mr. President
Lady Gaga
as La Camaleón
Antonio Banderas
as El Camaleón 4
Walton Goggins
as El Camaleón 1
Cuba Gooding Jr.
as El Camaleón 2
Vanessa Hudgens
as Cereza
Alexa PenaVega
as Killjoy
Marko Zaror
as Zaror
Tom Savini
as Osiris Amanpour
William Sadler
as Sheriff Doakes
Julio Oscar Mechoso
as Chepo
Callie Hernandez
as Space Babe
Billy Blair
as Billy Blair
Samuel Davis
as Clebourne
Jason Christopher
as Lieutenant Brass
D.H
David C. Heard
as Doctor Villachez
C.R
Carlos Rodriguez
as Messenger
J.Z
Juan Zuani
as Radio Announcer (voice)
Emmy Robbin
as Pris
Jimmy Gonzáles
as Man in Bondage
P.B
Pablo Bracho
as Bartender Carlos
Ashley Wood
as Male Tourist
Patricia Vonne
as Female Tourist
Vincent Fuentes
as Cabrito Cook
R.D
Rick Delgado
as Police Captain
D.A
Daniel Arellano
as Elderly Attendant
Elle LaMont
as Dollface
E.R
Eduardo Renteria
as Doctor Goodbar
Pablo Esparza
as Grasa
R.T
Robert Tamayo
as Stuttering Tito
F.S
Felix Sabates
as Doc Felix
Edgar Arreola
as Estoban
Jorge A. Jimenez
as Dying Cartel Guy
A.A
Alejandro Antonio
as Boss of Mendez
Sam Medina
as Cartel Leader
Crystal Martinez
as Wife of Mendez
Electra Avellan
as Nurse Mona
Elise Avellan
as Nurse Lisa
Marci Madison
as Nurse Fine
Corey Burton
as Trailer Voice Guy (voice)
Elon Musk
as Elon Musk
Jessica Alba
as Sartana Rivera (uncredited)
J.J. Perry
as Voz's Henchman (uncredited)
Alexander Rodnyansky
as Radio Guest (uncredited)
