Bing Crosby

as Dr. James 'Jim' Pearson

Joan Caulfield

as Trudy Mason

Barry Fitzgerald

as Dr. Joseph McRory

Wanda Hendrix

as Emily Walters

Frank Faylen

as Bill Walters

Elizabeth Patterson

as Mrs. Gilley

Robert Shayne

as Roy Chesley

Larry Young

as Dr. Ronnie Jenks

Percy Kilbride

as Nat Dorkas

Charles Dingle

as Charles 'C.J.' Chesley

Don Beddoe

as Mort Elkins

Thurston Hall

as Congressman Beeker (uncredited)

Lillian Bronson

as Miss Lennek

Mary Field

as Secretary

Paul Stanton

as Mr. Daniels

Patrick McVey

as Ed Chanock

Richard M. Norman

Frank Ferguson

as Crane (uncredited)

Margaret Field

as Photo of Cousin Hattie (uncredited)

Milton Kibbee

as Ben - Bus Driver (uncredited)

Charles Middleton

as Farmer Pinkett (uncredited)

Clarence Muse

as Clarence, Train Waiter (uncredited)

Caren Marsh

as Wife