Charlie Sheen

as Dex Dogtective (voice)

Hilary Duff

as Sunshine Goodness (voice)

Eva Longoria

as Lady X (voice)

Wayne Brady

as Daredevil Dan (voice)

Christopher Lloyd

as Mr. Clipboard (voice)

Chris Kattan

as Polar Penguin (voice)

Larry Miller

as Vlad Chocool (voice)