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Cast (86)
Chris Rock
as Osmosis Jones (voice)
Laurence Fishburne
as Thrax (voice)
David Hyde Pierce
as Drix (voice)
Brandy Norwood
as Leah (voice)
Elena Franklin
as Shane Detorre
Bill Murray
as Frank Detorre
William Shatner
as Mayor Phlegmming (voice)
Ron Howard
as Tom Colonic (voice)
Kid Rock
as Kidney Rock (voice)
Molly Shannon
as Mrs. Boyd
Chris Elliott
as Bob
Jonathan Adams
as Officer Tom (voice)
Carlos Alazraqui
as Spanish Germ (voice)
K.A
Keith Anthony
as Additional Character Voices (voice)
Eddie Barth
as Conductor (voice)
Sally Brooks
as Additional Character Voices (voice)
Rodger Bumpass
as Joe Cramp / Announcer for Nerve News Network (voice)
M.C
Michael Carven
as Additional Character Voices (voice)
P.C
Paul Christie
as Dan Matter / Germ (voice)
Janis Dardaris
as Additional Character Voices (voice)
W.D
Wendy Dillon
as Additional Character Voices (voice)
Antonio Fargas
as Chill the Flu Shot (voice)
E.F
Eddie Frierson
as Frank Police Department Officer (voice)
Donald Fullilove
as Doughnut (voice)
Jackie Gonneau
as Additional Character Voices (voice)
S.G
Shannon Gregory
as Additional Character Voices (voice)
Richard Steven Horvitz
as Additional Character Voices (voice)
Rif Hutton
as Charlie (voice)
A.K
Art Kimbro
as Additional Character Voices (voice)
J.K
Joyce Kurtz
as Additional Character Voices (voice)
Anne Lockhart
as Female Red Blood Cell (voice)
Sherry Lynn
as Trudy (voice)
Danny Mann
as Musician Cell (voice)
Mickie McGowan
as Brain Librarian (voice)
K.O
Kenny Olson
as Kidney Rock Band (voice)
J.K
Jason Krause
as Kidney Rock Band (voice)
J.C
Joe C.
as Kidney Rock Band (voice)
S.E
Stefanie Eulinberg
as Kidney Rock Band (voice)
J.B
Jimmie Bones
as Kidney Rock Band (voice)
U.K
Uncle Kracker
as Kidney Rock Band (voice)
Joel Silver
as Police Chief (voice) (uncredited)
D.O
David Ossman
as Scabies (voice) (uncredited)
John Melendez
as Artie (voice)
Héctor Mercado
as Additional Character Voices (voice)
Paul Pape
as Male Red Blood Cell #2 (voice)
M.P
Marilyn Pasekoff
as Additional Character Voices (voice)
Chris Phillips
as Firefighter Doug (voice)
L.R
Lynne Redding
as Additional Character Voices (voice)
Al Rodrigo
as Frank Police Department Walkie Talkie (voice)
Herschel Sparber
as Bruiser (voice)
D.S
Doug Stone
as Police Officer Jamie (voice)
S.S
Steve Susskind
as Mob Boss Germ (voice)
Keri Tombazian
as Additional Character Voices (voice)
Paul Tuerpe
as Additional Character Voices (voice)
Robert Wisdom
as Big Germ (voice)
Danny Murphy
as Zookeeper Superintendent
J.M
Jack McCullough
as Zookeeper
W.D
Will Dunn
as Oyster Boy
Jackie Flynn
as School Janitor
K.J
Kelsey Jordan
as Bus Girl #1
Abe Farrelly
as Bus Girl #2
J.P
Jesse Peter
as Laughing Boy
John-Eliot Jordan
as Pea Soup Manager
N.B
Nancy Byers
as Pea Soup Supervisor
Kevin J. Flynn
as Docky's Clamshack Waiter
Sean Gildea
as Dreamy Photographer
K.F
Kathryn Frick
as Nurse #1
Nikki Tyler-Flynn
as Nurse #2
E.J
Elizabeth Jordan
as Nurse #3
Zen Gesner
as ER Doctor #1
M.H
Marc Hyman
as ER Doctor #2
Zak Penn
as ER Doctor #3
D.C
Diane Conrad
as Zoo Visitor or Staff
J.C
Judith Conrad
as Zoo Visitor or Staff
T.J
Thomas Jordan
as The Zoo Visitor or Staff
S.J
Sydney J. Bartholomew Jr.
as Zoo Visitor or Staff
E.J
Erica Johnson
as Zoo Visitor or Staff
B.C
Bo Cleary
as Pea Soup Staff
B.M
Bruce McIntyre
as Pea Soup Staff
C.O
Colleen O'Donnell
as Docky's Clamshack
D
Docky
as The Bikini Gang
J.M
Joe Murphy
as The Bikini Gang
B.M
Brian Mone
as Police Officer
S.F
Sean Fitzgerald
as Police Officer
G.C
Grace Costa
as ER Nurse
E.O
Emily O’Donnell
as School Girl
