Matthew Broderick

as Taylor Peters

Brittany Snow

as Amanda

Maura Tierney

as Lorraine Mendon

Peter Facinelli

as Greg

Steve Coogan

as Michael Henry

Ed Begley Jr.

as Self

Bill Fagerbakke

as Larry

Patrick Fischler

as Kevin - TV Executive

Daniel Roebuck

as Link

Lester Speight

as BV

J.P. Manoux

as Tony Clark

Katy Mixon

as Girl #1 with Greg

Peggy J. Scott

as Sharon the Maid

Jennifer Rau

as Whisper

Allan Wasserman

as Dr. Chase

Jenni Blong

as Paula

Signe Kiesel

as Dealer at Casino

Allie McCulloch

as Eve

Anthony Holiday

as Arco

Atticus Todd

as Gene

Victoria De Mare

as Hot Club Goer #1 (uncredited)

Sean T. James

as Insulting John (uncredited)

Kate Micucci

as Thin Girl (uncredited)

Vitta Quinn

as Vegas Hooker (uncredited)

Michael Proctor

as Hot Guy (uncredited)