Jason Biggs

as Tom Willoman

Eva Longoria

as Rebecca Seabrook

Rob Corddry

as Harper Billings

Monica Potter

as Laura Buchwald

Will Sasso

as Jesse Buchwald

Nat Faxon

as Turner Abernathy

Jill Latiano Howerton

as Nurse Gretchen

Kyle Gass

as Decatur Doublewide

Hayes MacArthur

as Digdug O'Shaughnessy

Ryan Whitney

as Carlotta

Zachary Gordon

as Frankie Fowler

Ed Helms

as Maurice

Kiernan Shipka

as Sarah

Nadji Jeter

as Sling Shot Kid

Uriah Shelton

as Prep School Kid

Miranda May

as Sheila (uncredited)

Allen Alvarado

as Miguel (uncredited)

Alejandro Patiño

as Helado

Patricia Belcher

as Colette Bamboo