Jamal Woolard

as Christopher 'Biggie' Wallace

Derek Luke

as Sean 'Puffy' Combs

Naturi Naughton

as Lil' Kim

Anthony Mackie

as Tupac "2Pac" Shakur

Antonique Smith

as Faith Evans

Angela Bassett

as Voletta Wallace

Marc John Jefferies

as Lil Cease

Sean Ringgold

as Suge Knight

C.J. Wallace

as Biggie (age 8-13)

Dennis L.A. White

as Damion 'D-Roc' Butler

Mohamed Dione

as Record Executive at Party

Menyone DeVeaux

as Hot Girl

Ginger Kroll

as Debbie

Ricky Smith

as Wally

Amanda Christopher

as Keisha

Jasper Briggs

as Damion (age 8-13)

Cyrus Farmer

as Selwyn

David Costabile

as Mr. Webber

Julia Pace Mitchell

as Jan

Taylor Dior

as Tyanna Wallace - Age 2

Aunjanue Ellis-Taylor

as Sandy

Edwin Freeman

as Mister Cee