Rob Lowe

as Paul Turner

Julie Bowen

as Peaches O'Dell

Saffron Burrows

as Sophia Becker

Jennifer Morrison

as Angela Anderson

David Harbour

as Stephen Green

Eric McCormack

as Larry Becker

Carrie-Anne Moss

as Penelope Nelson

Amanda Crew

as Helena St. John

Richard Schiff

as Dimitris Vargas

Lisa Pepper

as Amy

Jenica Bergere

as Molly

Chris Mulkey

as Roger Fillmore

Brooke Newton

as Tawny Shearson

Jamie Chung

as Kerstin Rhee

Ella Dershowitz

as Ariel Becker

Eddie George

as Tony Blanchard

Michelle Krusiec

as Shannon Haung

Frankie Shaw

as Samantha

Sarah Poynter

as Daisy Green

Kurt Yaeger

as Oliver Kennedy

Sara Mornell

as Janice

Davey Havok

as Jimmy McSorley

Brandon Scott

as Max

Rosalind Chao

as Kate - Focus Group Moderator

Ryan Alosio

as Johnny Duncan

David Fine

as Tommy

Melissa Stephens

as Christina - Kentucky Club Dancer

Elizabeth Wagner

as Kentucky Newscaster

Cynthia Popper

as Kentucky TV Reporter

Dan Rubin

as Skip Richards

Mark Plutynski

as Trip Simmons

Tina D'Elia

as Boston Waitress

Michael Song

as Grocer

Luke Rampersad

as Barista

Shirley Manson

as Nicole (uncredited)

Deanna Marks

as Amy (uncredited)

Jeffrey Moon

as Doctor (uncredited)

Maura Mannle

as Penelope's Friend (uncredited)

Toni Staniewicz

as Penelope's Aide (uncredited)

Jimmy Giliberti

as Journalist (uncredited)

Bobby Hollingsworth

as News Photographer (uncredited)