Edmond O'Brien

as John Vickers

Dean Jagger

as Sam Quade

Forrest Tucker

as Sgt. O'Hara

Polly Bergen

as Molly Quade

Harry Carey, Jr.

as Capt. Gregson

James Millican

as Général George Armstrong Custer

Douglas Spencer

as Kelso

Wallace Ford

as Pvt. 'Irish' Potts

Paul Fix

as Pvt. Fiore

Louis Jean Heydt

as Herb Woodson

Paul Lees

as Cpl. Stockbridge

Walter Sande

as Sgt. Parker

Charles Dayton

as Lt. Nelson

Robert Bray

as Maj. Comstock

James Burke

as Oldtimer

Chief Yowlachie

as Chief

John Mansfield

as Sub-chief

Monte Blue

as First Emigrant

Frank Ferguson

as Marshal

Cliff Clark

as Bartender

Paul E. Burns

as Bum

Charles Stevens

as Courier

John Hart

as Sgt. Plennert

Ray Teal

as Maj. Reno (uncredited)