Steve Antin

as Monkey Zetterland

Patricia Arquette

as Grace

Sandra Bernhard

as Imogene

Sofia Coppola

as Cindy

Tate Donovan

as Brent Zetterland

Rupert Everett

as Sasha

Katherine Helmond

as Honor Zetterland

Bo Hopkins

as Mike Zetterland

Ricki Lake

as Bella the Stalker

Debi Mazar

as Daphne

Martha Plimpton

as Sofie

Robin Antin

as Waitress in Canters

Frances Bay

as Grandma

Luca Bercovici

as Boot Guy

Chuck Grieve

as Guy at Taco Stand

Lance Loud

as Psychiatrist

Nicholas Matus

as Young Monkey

Chris Nash

as Policeman

Lou Pearlman

as Warden / Observation Psychiatrist

Blair Tefkin

as Brent's Assistant

Marc Lafia

as Observation Psychiatrist

Melissa Sullivan

as Observation Psychiatrist

Lauren Zuckerman

as Observation Psychiatrist

Reuven Russell

as CPR Rabbi (uncredited)

Vivian Schilling

as Network Producer (uncredited)