Will Estes

as Jonny Quest

Ed Gilbert

as Commander

Meredith MacRae

as Dr. Rachel Quest

George Hearn

as President

Anndi McAfee

as Jessie Kenyon (Bannon)

Don Messick

as Dr. Benton C. Quest / Bandit

Rob Paulsen

as Hadji

Whit Hertford

Pepe Serna

as Agent Menendez

Peter Renaday

as Dr. Victor Devlon

Jeffrey Tambor

as Dr. Zin

Marcelo Tubert

as Chef

Granville Van Dusen

as 'Race' Bannon

B.J. Ward

as 3-DAC

Frank Welker

as Snipe / Replicants