Daveigh Chase

as Lilo (voice)

Chris Sanders

as Stitch / Leroy (voice)

Tia Carrere

as Nani (voice)

Zoe Caldwell

as Grand Councilwoman (voice)

Kevin McDonald

as Pleakley (voice)

Kevin Michael Richardson

as Gantu (voice)

Rob Paulsen

as Reuben (voice)

Jeff Bennett

as Hamsterviel (voice)

David Ogden Stiers

as Jumba (voice)

Tara Strong

as Angel / Belle / Houdini / Pleakley's GACC Assistant (voice)

Debra Rogers

as First Officer Ombit (voice)

Ving Rhames

as Cobra Bubbles (voice)

Liliana Mumy

as Mertle Edmonds (voice)

Frank Welker

as Sparky / Sprout / Mr. Stenchy / Kixx / Hoilo / Slugger (voice)

Nancy Cartwright

as Shortstuff / Phantasmo (voice)

Bobcat Goldthwait

as Nosy (voice)

Doug Stone

as Ensign Getco (voice)

Tress MacNeille

as Bonnie / Poxy / Gigi / Topper / Felix / Melty / Amnesio / Cannonball / GACC Van Computer (voice)

Jim Cummings

as Heckler (voice) (uncredited)

Jillian Henry

as Elena (voice)

Lili Ishida

as Yuki (voice)

Rocky McMurray

as Clyde (voice)

Kali Whitehurst

as Teresa (voice)