Kate Higgins

as Frankie Stein (voice)

Salli Saffioti

as Cleo de Nile / Clawdeen Wolf (voice)

Debi Derryberry

as Draculaura (voice)

Laura Bailey

as Lagoona Blue / Nora Bloodgood (voice)

Audu Paden

as Ghoulia Yelps / Slow Moe / Manny Taur (voice)

Ogie Banks

as Clawd Wolf (voice)

Yuri Lowenthal

as Bram Devein / Deuce Gorgon / Gil Webber / Mr. Rotter (voice)

Cam Clarke

as Heath Burns / Hoodude Voodude / Van Hellscream / Romulus (voice)

America Young

as Toralei Stripe / Howleen Wolf (voice)

Erin Fitzgerald

as Abbey Bominable / Spectra Vondergeist (voice)

Wendee Lee

as Nefera De Nile / Ms. Crabgrass (voice)

Cindy Robinson

as Jackson Jekyll / Holt Hyde / Gory Fangtell (voice)

Gigi Sarroino

as Operetta (voice)