Olympia Dukakis

as Judy Hillerman

Jim Gaffigan

as Sandie

Judy Greer

as Allison Burbage

Maggie Gyllenhaal

as Emme Keeler

Tom McCarthy

as Davie Burbage

Sharat Saxena

as Satish

Naseeruddin Shah

as Avinash aka "Avi"

Tony Shalhoub

as Dr. Trabulous

Stephen Colbert

as Principal Peersall

Dick Latessa

as Jerry Binder

Will Arnett

as Danny Keeler

Seth Gilliam

as Clayton

Anita Gillette

as Lainie

Julie Dretzin

as Julie Driscoll

Edie Falco

as Safarah Polsky

Jim Parsons

as Justin

Rosemarie DeWitt

as Debbie

Alexis Dziena

as Angie (scenes deleted)