Gérard Depardieu

as Obélix

Clovis Cornillac

as Astérix

José Garcia

as Couverdepus

Franck Dubosc

as Assurancetourix

Stéphane Rousseau

as Alafolix

Jean-Pierre Cassel

as Panoramix

Mónica Cruz

as Esmeralda

Alain Delon

as Jules César

Benoît Poelvoorde

as Brutus

Vanessa Hessler

as Princess Irina

Michael Herbig

as Pasunmotdeplus

Santiago Segura

as Doktormabus

Bouli Lanners

as King Aderlas

Adriana Karembeu

as Madame Methusalix

Jérôme Le Banner

as Claudius Muscullus

Alexandre Astier

as Obstinatus

Luca Bizzarri

as Alpha

Paolo Kessisoglu

as Beta

Élie Semoun

as Omega

Francis Lalanne

as Lalanix

Michael Schumacher

as Schumix

Zinédine Zidane

as Numérodis

Tony Parker

as Tonus Parker

Sim

as Agecanonix

Patrice Thibaud

as Coach

Stéphane De Groodt

as Numerix

Nathan Jones

as Humungus

Dany Brillant

as Le goûteur de miroir

Vincent Moscato

as Le lutteur de la délégation de Rhodes

Dorothée Jemma

as Bonemine

Tony Gaultier

as Ordralfabétix

Pierre Tchernia

as Le narrateur (voice)

Enrico Brignano

as Commentatore sportivo

Jean Todt

as il padrone di Schumix

Jamel Debbouze

as Numérobis (uncredited)

David M. Antón

as Romano