Freddie Highmore

as Arthur Montgomery

Mia Farrow

as Granny

Logan Miller

as Jake

Robert Stanton

as Armand

Penny Balfour

as Rose Montgomery

Ron Crawford

as Archibald

Jean Bejote Njamba

as Chief Matassalai (voice)

Lou Reed

as Maltazard (voice)

Selena Gomez

as Selenia (voice)

Jimmy Fallon

as Prince Betameche (voice)

Snoop Dogg

as Max (voice)

Fergie

as Replay (voice)

will.i.am

as Snow (voice)

Jean-Paul Rouve

as Le père (voice)