Glenn Close

as Marcia Zarrow

K. Todd Freeman

as Joe

Jessica Hecht

as Jill

Gretchen Mol

as Sarah

Tim Blake Nelson

as Adam Zarrow

Gloria Reuben

as Meredith

Kristen Stewart

as Sophie

Corey Stoll

as Sam

Mickey Sumner

as Nicole

Sam Waterston

as Prof. Walter Zarrow

Yul Vazquez

as Dr. Edward Barnes

Michael Kenneth Williams

as Jeffrey

Jacqueline Baum

as Allie

Lisa Benavides

as Dr. Pratt

Katie Chang

as Amy

Philip Ettinger

as Roger

Ben Konigsberg

as Hal

Hannah Marks

as Ella Zarrow

Richard Thomas

as Mr. Werth

Natasha Gregson Wagner

as Marta

J. Bernard Calloway

as Cedar Lemons

Rob Morgan

as Parnell

David Aaron Baker

as Devlin

Scott Cohen

as Dr. Laffer

Lucas Hedges

as Greg

Ivan Goris

as Ignacio

Julia Morrison

as Shani

Annie Parisse

as Rachel

Christopher McCann

as Dr. Keller

Ekaterina Samsonov

as Angie

Lee Wilkof

as Ray Eisenberg

Patrick Kerr

as Jerry

G. Michelle Robinson

as Gracie

Keith Randolph Smith

as Judge

Cliff Moylan

as Bailiff

Denise Burse

as West Indian Nurse

Derrick Baskin

as Medical Examiner

Marcus Callender

as Medical Assistant

Erica Cho

as Teacher

Cameron Taylor

as Nurse

Erika Rose

as Waitress

Nina Rosenthal

as Waitress

Casey Roberts

as Student

Ana Marie Calise

as Student

Doris McCarthy

as Diner Lady (uncredited)

Korey Jackson

as Actor

Kaipo Schwab

as Tenant

Zenon Zeleniuch

as Hospital Visitor