Stephen Tyrone Williams

as Dr. Hess Green

Zaraah Abrahams

as Ganja Hightower

Rami Malek

as Seneschal Higginbottom

Elvis Nolasco

as Lafayette Hightower

Thomas Jefferson Byrd

as Bishop Zee

Joie Lee

as Nurse Colquitt

Felicia Pearson

as Lucky Mays

Steven Hauck

as Dr. Wood

Lauren Macklin

as Nurse Royster

Stephen McKinley Henderson

as Deacon Yancy

Jeni Perillo

as Sahara Paysinger

Katherine Borowitz

as Ms. Staples

Donna Dixon

as Ms. Blair

Chiz Schultz

as Dr. Redding

Rafael Osorio

as Doorman Clemente

Cinqué Lee

as Ellington Christopher

Lil Buck

as Jookin' Dancer

Naté Bova

as Tangier Chancellor

Al Palagonia

as Jet Concierge / Dom Pagnotti

Quincy Tyler Bernstine

as Usherette / Sister Hazel

Kayinde J. Harris

as Usherette / Sister Gwen

Siedah Garrett

as Private Jet Stewardess