Kevin Carlson

as Timmy the Tooth / Darol (voice)

Todd Mattox

as Brushbrush (voice)

Cheryl Blaylock

as Bubbles Gum / Dee (voice)

Michael Earl

as Miss Flossie (voice)

James Murray

as The Cavity Goon (voice)

Bruce Lanoil

as Miss Sweety / Sidney Cyclops (voice)

Christine Papalexis

as Annette Bruner Prower / Nicki / Irene (voice)

Allan Trautman

as Johnny Paste / Sunny the Sun / Leo (voice)

Phil Baron

as Mr. Wisdom / Nolan (voice)

Dina Fraboni

as Kay (voice)