Frank Welker

as Scooby-Doo / Fred Jones (voice)

Mindy Cohn

as Velma Dinkley (voice)

Grey DeLisle

as Daphne Blake (voice)

Matthew Lillard

as Shaggy Rogers (voice)

Gabriel Iglesias

as Professor Perez (voice)

Carlos Alazraqui

as Brazillian Player (voice)

Andrew Kishino

as Security Guard (voice)