Tom Hanks

as Narrator (voice)

Bill Paxton

as Ed Mitchell (voice)

Morgan Freeman

as Neil Armstrong (voice)

Scott Glenn

as Charles Duke (voice)

Paul Newman

as Dave Scott (voice)

John Travolta

as Jim Irwin

Matthew McConaughey

as Al Bean (voice)

Matt Damon

as Al Shepard (voice)

Bryan Cranston

as Buzz Aldrin (voice)

Rick Gomez

as Alpha Station Commander (voice)

Colin Hanks

as Conspiracy Neil Armstrong

Frank John Hughes

as Future Houston Capcom

Neal McDonough

as Reservoir Commander

Barry Pepper

as John Young

Kevin Pollak

as Director

Julie Shimer

as Future Astronaut

Gary Sinise

as Gene Cernan

Peter Scolari

as Pete Conrad

Donnie Wahlberg

as Helium 3 Commander

Rita Wilson

as Beta Station Commander