Mike O'Malley

as Darryl MacPherson (voice)

Julia Sweeney

as Wanda MacPherson (voice)

Joel Murray

as Carl Bitterman (voice)

Kath Soucie

as Rodney Bitterman / Megan Bitterman (voice)

Arabella Field

as Melinda Bitterman (voice)

Diedrich Bader

as Kenny (voice)

Nicole Sullivan

as Bizzy (voice)

Jim Cummings

as Hugh Wisowski / Kris (voice)

E. G. Daily

as Zoe (voice)

Maurice LaMarche

as Additional Voices (voice)

Phil LaMarr

as Rex (voice)

Wendy Raquel Robinson

as Josie / Madge (voice)