Susan Sarandon

as Marnie Minervini

Rose Byrne

as Lori Minervini

J.K. Simmons

as Randall Zipper

Cecily Strong

as Jillian

Jerrod Carmichael

as Freddy / Fredo

Michael McKean

as Mark

Jason Ritter

as Jacob

Billy Magnussen

as Ben

Lucy Punch

as Emily

Sarah Baker

as Elaine

Amy Landecker

as Diane

Casey Wilson

as Trish

Harry Hamlin

as TV Dad

Laura San Giacomo

as TV Mom

Megalyn Echikunwoke

as Elise

Lou Volpe

as Dom

Tony Amendola

as Tony

Robert Picardo

as Cos

Irina Maleeva

as Angie

Tehya Santos

as Tehya

Rebecca Drysdale

as Dani

Randall Park

as Officer Lee

Bill Fagerbakke

as Officer Davis

Marques Ray

as Officer Bernie

Corey Reynolds

as Officer Wells

Shiri Appleby

as TV Daughter

Daniel Maurio

as TV Director

Beverly Mitchell

as Tina

Despina Demetriou

as Pina

Luanne Crawford

as Emily's Mom