Dick Van Dyke

as Dr. Mark Sloan

Cynthia Gibb

as Dr. Amanda Bentley

Stephen Caffrey

as Dr. Jack Parker

Barry Van Dyke

as Det. Steve Sloan

Mariette Hartley

as Kate Hamilton

Peter Scolari

as Dr. Zach Drummond

David Warner

as Dr. Lloyd Stern

Kerrie Keane

as Maggie Drummond

George Hamilton

as J.D. Gantry / Harry Lennox

Ron White

as Webber Lyman / John Harwin

Christianne Hirt

as Justine Whitaker

Debi A. Monahan

as Breast Implant Patient

Vernee Watson

as Esther Wiggins

Sheila Paterson

as Mrs. Thibideaux

Beverley Hendry

as Lindsay

Jed Dixon

as Jimmy

Jano Frandsen

as Harry Lennox

A.C. Peterson

as Bruiser

Dave 'Squatch' Ward

as Gorilla

Johnny Cuthbert

as Vinnie

Ken Kramer

as Bearded Man

Cusse Mankuma

as Clerk

Jill Muncaster

as Waitress at Hotel

Wendy Van Riesen

as Hysterical Patient

Deryl Hayes

as Police Officer

William Buck

as Minister