Mel Blanc

as Barney Rubble / Dino / Mr. Spacely (voice)

Daws Butler

as Elroy Jetson / W.C. Cogswell / Henry Orbit (voice)

Don Messick

as Astro / R.U.D.I / Mac / Announcer / Store Manager / Robot (voice)

Henry Corden

as Fred Flintstone / Knight (voice)

Jon Bauman

as Iggy (voice)

Hamilton Camp

as Turk Tarpit (voice)

Julie McWhirter

as Betty Rubble / Jet Rivers / Investor / Panelist / Harem Girl (as Julie Dees) (voice)

George O'Hanlon

as George Jetson (voice)

Penny Singleton

as Jane Jetson (voice)

John Stephenson

as Mr. Slate / Moderator / Investor / Poker Player (voice)

Brenda Vaccaro

as Didi (voice)

Jean Vander Pyl

as Wilma Flintstone / Rosie / Mrs. Spacely (voice)

Janet Waldo

as Judy Jetson / Female Computer (voice)

Frank Welker

as Dan Rathmoon / Johnny / Mr. Goldbrick (voice)

Patric Zimmerman

as (voice)