Debi Derryberry

as Jimmy Neutron (voice)

Tara Strong

as Timmy / School Girl (voice)

Rob Paulsen

as Carl / Anti-Fairy Walla (voice)

Jeffrey Garcia

as Sheen / Anti-Fairy Walla (voice)

Carolyn Lawrence

as Cindy Vortex (voice)

Crystal Scales

as Libby Folfax (voice)

Frank Welker

as Goddard (voice)

Susanne Blakeslee

as Wanda / Mom / Anti-Wanda / Anti-Fairy #1 (voice)

Daran Norris

as Cosmo / Dad / Jorgen Von Strangle / Anti-Cosmo (voice)

Carlos Alazraqui

as Mr. Crocker (voice)

Dee Bradley Baker

as Binky (voice)

Gary LeRoi Gray

as A.J. (voice)

Jim Ward

as Chet Ubetcha / Anti-Fairy #2 (voice)

Jeff Bennett

as Dr. Moist (voice)

Kevin Michael Richardson

as Morgan Freeman / Anti-Fairy Walla (voice)

Tim Curry

as Professor Calamitous (voice)

Grey DeLisle

as Vicky (voice)