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Cast (83)
Will Ferrell
as Sherlock Holmes
John C. Reilly
as Dr. John Watson
Rebecca Hall
as Dr. Grace Hart
Kelly Macdonald
as Mrs. Martha Hudson
Rob Brydon
as Inspector Lestrade
Lauren Lapkus
as Millie
Pam Ferris
as Queen Victoria
Ralph Fiennes
as Prof. James Moriarty / Jacob Musgrave
Adam Scherr
as Brawn
Kieran O'Brien
as PC Smalls
Noah Jupe
as Doxy
Bella Ramsey
as Flotsam
C.M
Colby Mulgrew
as Haybag
Scarlet Grace
as Pickle
Billy Jenkins
as Mud Fog
Michael Culkin
as The Judge
Jana Pérez
as Lestrade's Wife
Wolf Roth
as Sigmund Freud
N.O
Nathan Osgood
as Mark Twain
D.S
David Shackleton
as Albert Einstein
Paul Cassidy
as Charlie Chaplin
Ben Lee
as Houdini
Bronson Webb
as Jonathan Nightingale
J.M
Jamie-Rose Monk
as Mrs. Nightingale
Billy Zane
as Billy Zane
Jason Thorpe
as Butler
Robert Cawsey
as Waiter
S.E
Stanley Eldridge
as Waiter
Oliver Maltman
as Telegraph Operator
David Stoller
as Hudson's Guard
J.R
Jack Riley
as Newschild
Lilly Aspell
as Newschild
Ethan Rouse
as Newschild
E.E
Ellie Rose Eames
as Newschild
Jamie Baughan
as Titanic Ship Officer Liaison
H.D
Helen Duff
as Titanic Guest
Jess Liaudin
as Hangman
W.K
Wesley Kent-Hargreaves
as Weird Child Companion
Daniel Fearn
as Drooling Man Companion
D.L
Darren Lake
as Disorientated Man Companion
Martin Bishop
as Priest
Gerard Monaco
as Titanic Ship Officer
Michael Buffer
as Fight Fan #1
Bruce Buffer
as Fight Fan #2
Russell Wilcox
as Announcer
Hector Bateman-Harden
as Young Sherlock Holmes
Codie-Lei Eastick
as Young Watson
Laura Stevely
as Sherlock's Mother
L.B
Layla Rose Boyce
as Nicotine Stains / Nancy
Sadie Newman
as Jane
H.B
Harry Baxendale
as Seamus
Ella Bright
as Bridgette
K.H
Kenneth Hadley
as Headmaster
Paul Bigley
as Teacher #1
Sue Maund
as Teacher #2
Tommy Gene Surridge
as Inky Hands
Paddy Holland
as Tough Kid
Hugh Laurie
as Mycroft Holmes (uncredited)
Steve Coogan
as Gustav Klinger (uncredited)
Phil Hodges
as Mr. Algernon Barkworth (uncredited)
Sara Beasley
as Mrs. Frobisher (uncredited)
James Eeles
as Manager Mr. Petrucka (uncredited)
Paul T.T. Easter
as John (uncredited)
Jordan Long
as Herbert (uncredited)
S.S
Sonnyboy Skelton
as Doxy's Dad (uncredited)
W.D
Willem Dalby
as Newsie Man (uncredited)
Riley White
as Newsie Kid - Jimmy (uncredited)
Lochlan White
as Newsie Kid - Timmy (uncredited)
J.K
John Kinory
as Instructing Solicitor (uncredited)
B.L
Benjamin Lok
as Courtroom Person 3 (uncredited)
Joseph Macnab
as Fitness Instructor (uncredited)
Martin Bassindale
as One Man Band (uncredited)
A.O
Amelia O'Loughlin
as White Star-Line Girl (uncredited)
M.L
Matthew Di Liello
as Telly-Phone Assistant (uncredited)
C.L
Craig Thomas Lambert
as Yeoman of the Guard (uncredited)
Jorge Leon
as British Soldier (uncredited)
Martyn Mayger
as Buckingham Palace Guest (uncredited)
H.O
Hugh O'Brien
as Garden Party Guest (uncredited)
Deepak Anand
as Nobleman (uncredited)
Shawn Dixon
as Upper Class Gentleman #1 (uncredited)
A.R
Anthony Richard Rowe
as Victorian Gentleman (uncredited)
M.S
Mick Slaney
as Docker (uncredited)
K.F
Karl Farrer
as Russian Merchant (uncredited)
