John Neville

as Sherlock Holmes

Donald Houston

as Doctor Watson

John Fraser

as Lord Carfax

Anthony Quayle

as Doctor Murray

Barbara Windsor

as Annie Chapman

Adrienne Corri

as Angela

Frank Finlay

as Inspector Lestrade

Judi Dench

as Sally

Barry Jones

as Duke of Shires

Robert Morley

as Mycroft Holmes

Edina Ronay

as Mary Keller

Charles Regnier

as Joseph Beck

Cecil Parker

as Prime Minister

Georgia Brown

as Singer

Dudley Foster

as Home Secretary

Peter Carsten

as Max Steiner

Christiane Maybach

as Polly Nichols

Kay Walsh

as Cathy Eddowes

John Cairney

as Michael Osborne

Avis Bunnage

as Landlady

Barbara Leake

as Mrs. Hudson

Patrick Newell

as PC Benson

Norma Foster

as Liz Stride

Terry Downes

as Chunky

Jeremy Lloyd

as Rupert