Tom Kenny

as Ham / Reporter #1 (voice)

Zack Shada

as Comet (voice)

Patrick Warburton

as Titan (voice)

Cheryl Hines

as Luna (voice)

Carlos Alazraqui

as Houston / Piddles The Clown / Camera Guy (voice)

Laura Bailey

as Kilowatt / Computer Voice (voice)

John DiMaggio

as Zartog / Human #1 / Human #2 (voice)

Stanley Tucci

as Senator (voice)

Patrick Breen

as Dr. Bob (voice)

Jane Lynch

as Dr. Poole (voice)

Omid Abtahi

as Dr. Jagu / Reporter #2 (voice)

Noreen Reardon

as Alien #1 (voice)

David Michie

as Alien #2 (voice)