Christopher Lee

as Dr. Fu Manchu

Douglas Wilmer

as Nayland Smith

Horst Frank

as Rudy / Ronald "Ronny" Moss

Tsai Chin

as Lin Tang

Wolfgang Kieling

as Dr. Lieberson

Maria Rohm

as Ingrid Swenson

Howard Marion-Crawford

as Dr. Petrie

Suzanne Roquette

as Maria Lieberson

Noel Trevarthen

as Mark Weston

Tony Ferrer

as Insp. Ramos

Mona Chong

as Jasmin

Peter Carsten

as Kurt Heller

Eddie Byrne

as Ship's Captain

Christopher Casson