Sadie Stanley

as Kim Possible

Sean Giambrone

as Ron Stoppable

Ciara Riley Wilson

as Athena

Taylor Ortega

as Shego

Connie Ray

as Nana Possible

Issac Ryan Brown

as Wade

Erika Tham

as Bonnie Rockwaller

Maxwell Simkins

as Young Drakken

Christy Carlson Romano

as Poppy Blu

Nancy Cartwright

as Rufus (voice)

Patton Oswalt

as Professor Dementor

Todd Stashwick

as Dr. Drakken

Alyson Hannigan

as Dr. Ann Possible

Matt Clarke

as James Timothy Possible

Owen Fielding

as Tim

Connor Fielding

as Jim

Michael P. Northey

as Mr. Barkin

Patrick Sabongui

as Dr. Glopman

Cedric Ducharme

as Cool Todd

Kelcey Mawema

as Student #1

Serena Crouse

as Student #1

Karissa Ketter

as Student #2

Julian Nathan Lokash

as Nerdy Kid

Nakai Takawira

as Small Girl

Aliza Vellani

as Gossiping Mom

Javier Lacroix

as Bus Driver