Audrey Wasilewski

as Chef Sue / Librarian (voice)

Frank Welker

as Scooby-Doo / Fred Jones (voice)

Giada De Laurentiis

as Giada De Laurentiis (voice)

Salli Saffioti

as Reporter / Nancy Metcalf (voice)

Matthew Lillard

as Shaggy Rogers (voice)

Grey DeLisle

as Daphne Blake (voice)

Kate Micucci

as Velma Dinkley (voice)

Bobby Flay

as Bobby Flay (voice)

Jason Spisak

as Bradley Bass (voice)

Dana Snyder

as Skip Taylor (voice)

Marcus Samuelsson

as Marcus Samuelsson (voice)

Jim Cummings

as Jeremiah Noseworthy (voice)