Matt Ryan

as John Constantine / Constantine-Demons (voice)

Robin Atkin Downes

as Nergal (voice)

Laura Bailey

as Trish / Asa the Healer (voice)

Rachel Kimsey

as Angela (voice)

Jim Meskimen

as Beroul / Cheleb / Quedbas (voice)

Emily O'Brien

as Renee Chandler (voice)

Damian O'Hare

as Chas Chandler / Amainon / Decarabia (voice)

Kevin Michael Richardson

as Mahonin / Old Man (voice)

Rick D. Wasserman

as Mictlantecuhtli (voice)