James Denton

as Superman / Clark Kent (voice)

Christina Hendricks

as Lois Lane (voice)

Anthony LaPaglia

as Lex Luthor (voice)

Ed Asner

as Perry White (voice)

Linda Cardellini

as Nasthalthia Luthor (voice)

Matthew Gray Gubler

as Jimmy Olsen (voice)

Arnold Vosloo

as Bar-El (voice)

Frances Conroy

as Martha Kent (voice)

John DiMaggio

as Samson / Ultra-Sphinx (voice)

Alexis Denisof

as Dr. Leo Quintum (voice)

Chris Cox

as Lead Agent (voice)

Steve Blum

as Atlas / General Sam Lane / Astronaut #1 (voice)

Obba Babatundé

as Judge / Bibliobot (voice)

Robin Atkin Downes

as Solaris (voice)

Michael Gough

as Parasite (voice)

Finola Hughes

as Lilo (voice)

Kevin Michael Richardson

as Steve Lombard / Lizard Man / Convict (voice)

Fred Tatasciore

as Krull / Robots / Astronaut #2 (voice)

Cathy Cavadini

as Floral / Cat Grant (voice)