Kiefer O'Reilly

as Howard Lovecraft (Voice)

Jeffrey Combs

as H.P. Lovecraft (voice)

Tyler Nicol

as Winfield Lovecraft (voice)

Michelle Myers

as Sarah Lovecraft (voice)

Sean Patrick O'Reilly

as Spot / Cthulhu (voice)

Alison Wandzura

as Mary Lovecraft (voice)

Mark Hamill

as Dr. Henry Armitage (voice)

Vijary Vaibhav Saini

as Professor Jaswant Atwood (voice)

Ashleigh Ball

as Ellen Ellery (voice)

Scott McNeil

as Hamish Rice / Govlins (voice)

Nick Wolfhard

as William Dyer (voice)

Christopher Plummer

as Dr. Jeffrey West (voice)

Finn Wolfhard

as Herbert West (voice)

Doug Bradley

as Nyarlathotep (voice)

Summer O'Reilly

as Gotha (voice)

Harmony O'Reilly

as Innes (voice)

Phoenix O'Reilly

as Twi'i (voice)