Tom Hanks

as Larry Crowne

Julia Roberts

as Mercedes Tainot

Bryan Cranston

as Dean Tainot

Cedric the Entertainer

as Lamar

Pam Grier

as Frances

Taraji P. Henson

as B'Ella

George Takei

as Dr. Matsutani

Nia Vardalos

as Map Genie (voice)

Sarah Mahoney

as Samantha

Roxana Ortega

as Alvarez

Rami Malek

as Steve Dibiasi

Wilmer Valderrama

as Dell Gordo

Gugu Mbatha-Raw

as Talia

Grace Gummer

as Natalie Calimeris

Maria Canals-Barrera

as Lala Pinedo

Rita Wilson

as Wilma Q. Gammelgaard

Randall Park

as Trainee Wong

Holmes Osborne

as David Busik

Rob Riggle

as Jack Strang

Brady Rubin

as Dorothy Genkos

Sy Richardson

as Avery

Alex Quijano

as Team Leader #1

Tina Huang

as Team Leader #2

E-Kan Soong

as Team Leader #3

Tarina Pouncy

as Team Leader #4

Chet Hanks

as Pizza Delivery Boy

Erin Underwood

as Mom with baby

Carly Reeves

as Sal

Dale Dye

as Cox

Barry Sobel

as Cubby

Bob Stephenson

as Andrews

Ian Gomez

as Frank

Jon Seda

as Officer Diamond

Joshua Bitton

as Officer Baker

Sarah Levy

as Eli