Freddie Highmore

as George Zinavoy

Emma Roberts

as Sally Howe

Michael Angarano

as Dustin

Elizabeth Reaser

as Charlotte Howe

Alicia Silverstone

as Ms. Herman

Sasha Spielberg

as Zoe

Marcus Carl Franklin

as Will

Ann Dowd

as Mrs. Grimes

Blair Underwood

as Principal

Rita Wilson

as Vivian Sargent

Sam Robards

as Jack Sargent

Sophie Lane Curtis

as Chastity

Maya Ri Sanchez

as Cynthia

Ann Harada

as Mrs. Dougherty

Jarlath Conroy

as Harris McElroy

Andrew Levitas

as Javier

Dan Leonard

as Nick

Lindsay-Elizabeth Hand

as Sally's Friend (uncredited)

Joseph Ernest

as Student (uncredited)