Fess Parker

as John 'Doc' Grayson

Kathleen Crowley

as Laura Thompson

Jeff York

as Hank Brekenridge

David Stollery

as Dan Thompson

Sebastian Cabot

as Bissonette

George Reeves

as James Stephen

Doreen Tracey

as Bobo Stephen

Barbara Woodell

as Mrs. Stephen

John War Eagle

as Wolf's Brother

Cubby O'Brien

as Jerry Stephen

Tommy Cole

as Jim Stephen

Leslie Bradley

as Spencer Armitage

Morgan Woodward

as Obie Foster

Iron Eyes Cody

as Many Stars

Anthony Earl Numkena

as Little Thunder

Karen Pendleton

as Myra Thompson

Jane Liddell

as Ruth Benjamin

Jon Locke

as Ed Benjamin