Jeanne Moreau

as Marguerite de Valois, "La Reine Margot"

Armando Francioli

as Joseph Peyrac La Môle

Robert Porte

as Charles IX

Henri Génès

as Annibal de Coconas

Françoise Rosay

as Catherine de Médicis / Catharine of Medici

André Versini

as Henri de Navarre / Henry of Navarra

Fiorella Mari

as Henriette

Daniel Ceccaldi

as Henri d'Anjou

Louis de Funès

as René, l'astrologue

Louis Arbessier

as L'amiral de Coligny

Guy Kerner

as Le duc de Guise

Jean-Roger Caussimon

as Le gouverneur de la prison / Prison Governor

Jean Témerson

as L'aubergiste de 'La belle étoile'

Olivier Mathot

as Pierre

Jean Lanier

as Ambroise Paré

Robert Moor

as Le procureur

Jacques Eyser

as Caboche

Vittorio Sanipoli

as Maurevel, le chef de la police

René Blancard

Jean-Marie Bon

Jacques Bézard

Nicole Riche

as Gilonne

Patrizia Lari

as Carlotta

Jean Duval

André Collombet

Guy Saint-Clair

Georges Demas

as Un garde (uncredited)

Pierre Moncorbier

as Un huguenot (uncredited)

Pâquerette

as Une femme dans l'auberge (uncredited)

Serge Sauvion

as Le garde de la chapelle (uncredited)

Jean Thielment

as L'aide du bourreau (uncredited)

Marc Valbel

as Récitant/Narrator (uncredited)