Alicia Silverstone

as Goody

Krysten Ritter

as Stacy

Dan Stevens

as Joey

Richard Lewis

as Danny

Wallace Shawn

as Dr. Van Helsing

Justin Kirk

as Vadim

Malcolm McDowell

as Vlad Tepish

Sigourney Weaver

as Cisserus

Marilu Henner

as Angela

Kristen Johnston

as Mrs. Van Helsing

Zak Orth

as Renfield

Larry Wilmore

as Professor Quincy

Meredith Scott Lynn

as Rita

Brian Backer

as Middle-Aged Guy / Dentist

Taylor Negron

as Pizza Guy

Amir Arison

as Derek

Bettina Bresnan

as Maryanne Cachillio

Todd Barry

as Ivan

Glen Trotiner

as Leather Guy at Club

Emily Goldwyn

as Juicy Girl

Ivan Sergei

as Detective

Scott Thomson

as Erik

Johanna Went

as Rat Eating Woman

Rhonda Freya English

as Nurse 1

Leisa Pulido

as Landlady

Joel Michaely

as Nerdy Sales Guy

Mike Eshaq

as Gunman

Annie Kitral

as Elderly Woman

Thomas D. Mahard

as Elderly Man

Christopher Jarecki

as Legal Clerk

Olivia Walby

as Baby Goody

Gael García Bernal

as Diego Bardem (uncredited)