Freddie Highmore

as Arthur Montgomery

Madonna

as Princess Selenia (voice)

Mia Farrow

as Daisy Suchot

Adam LeFevre

as Davido

Doug Rand

as Arthur's Father

Penny Balfour

as Rose Montgomery

Ron Crawford

as Archibald Suchot

David Bowie

as Maltazard (voice)

David Suchet

as Narrator (voice)

Robert De Niro

as King (voice)

Snoop Dogg

as Max (voice)

Jean Bejote Njamba

as Chief Matassalai (voice)

Lee Delong

as Saleslady

Saul Jephcott

as Police Officer #1

Christian Erickson

as Antique Dealer

Eric Balliet

as Mover #1

Oxmo Puccino

as Mover #2

Robert William Bradford

as Baliff

Jerry Di Giacomo

as Repairman

Bienvenue Kindoki

as Matassalai #1

Valéry Koko Kingue

as Matassalai #2

Aba Koïta

as Matassalai #3

Vincent Mendy

as Matassalai #4

Mathar Licka Gueye

as Matassalai #5

Tonio Descanvelle

as Police Officer #2

Chazz Palminteri

as Travel Agent (voice)

Jimmy Fallon

as Betameche (voice)

Emilio Estevez

as Ferryman (voice)

Harvey Keitel

as Miro (voice)

Rob Corddry

as Seides (voice)

Nate Corddry

as Seides (voice)

Erik Per Sullivan

as Baby Bug / Mino (voice)

Anthony Anderson

as Koolomassai (voice)

Jason Bateman

as Darkos (voice)